Your skin is changing. Here's what the research says.
Skin starts changing in our 30s, and the shift picks up speed in our late 40s and 50s. It feels drier. It looks less firm. The products that worked for years suddenly don't.
It's not your imagination, and it's not your routine. Swansera is built around phytoestrogens, plant compounds from soy and red clover that researchers have studied on midlife skin for more than twenty years. We paired them with well-researched skin actives: bakuchiol, peptides, and ceramides. Below are the ingredients in our formula, followed by the published phytoestrogen studies that shaped it.
Clinically Studied Ingredients
Soy Isoflavones
Source of genistein & daidzein
Red Clover
Phytoestrogen-rich botanical
Wild Yam
Traditional botanical extract
Flax
Lignan & omega source
Ceramides
Barrier lipids that decline in midlife
Peptide Complex
Matrixyl® 3000 + Argireline®
Bakuchiol
Plant-based retinol alternative
Hyaluronic Acid
Deep hydration & moisture retention
Niacinamide
Supports barrier strength & even skin tone
Jojoba Oil
Nourishing lipid that supports skin softness
Green Tea
Antioxidant-rich botanical extract
Squalane
Skin-identical lipid for moisture
What the research shows
Three published clinical studies on plant compounds and midlife skin.
- Participants
- 50 postmenopausal women
- Design
- Randomized, double-blind
- Duration
- Six weeks, twice daily
- Arms
- Genistein vs. placebo
The genistein group showed improvement in hydration, pore appearance, and wrinkle measurements. The tested cream paired genistein with vitamin E, vitamin B3, and ceramides. Genistein comes from soy and red clover, both in our formula, which makes this the study closest to what's in our product.
- Participants
- 30 women
- Duration
- 24 weeks
- Measure
- Collagen, skin biopsy
- Arms
- Genistein vs. estrogen
Both groups built more collagen, the protein that keeps skin firm. The prescription estrogen cream produced a larger increase. Genistein still made a measurable difference, which is why plant compounds are a real option for women seeking a non-prescription approach.
- Participants
- 59 women, aged 40–70
- Population
- Most postmenopausal 3+ yrs
- Duration
- 12 weeks
- Formula
- 0.3% equol lotion
Across eight areas (firmness, smoothness, tone, lines, radiance, pore size, spots, and hydration), women reported 51–78% improvement over baseline. Equol isn't in our formula. The body makes it from daidzein, a soy compound that is in our product.
References
These studies tested plant compounds, not Swansera products. Swansera products are cosmetic and are not intended to diagnose, treat, cure, or prevent any disease.
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Na Takuathung M, et al. J Clin Med. 2023;12(4):1326.
doi.org/10.3390/jcm12041326 -
Lephart ED, Naftolin F. Dermatol Ther (Heidelb). 2021;11:53–69.
pmc.ncbi.nlm.nih.gov/articles/PMC7859014 -
Collagen concentration after topical estradiol and genistein. Gynecol Endocrinol. 2017;33(11).
pubmed.ncbi.nlm.nih.gov/28508697 -
Lephart ED. Bioactives for estrogen-deficient skin. Dermatol Ther (Heidelb). 2025.
link.springer.com/article/10.1007/s13555-025-01413-2